Anti-Blood group A antigen [AC1001]

Catalogue Number: AB04235-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:AC-1001
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: AC1001
Isotype: IgG1
Immunogen: The original antibody was produced by immunizing mice with A1 erythrocytes and with blood group A substance.
Application: ELISA, HA, Crstion

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody was used in a quantitative precipitin assay, a hemagglutination assay (HA), inhibition assays (by ELISA). In the HA with human erythrocytes, the antibody reacted with the A1 and A2 subtypes (showing double the sensitivity towards the A1 subtype) (Chen and Kabat, 1985; PMID: 2414276). The structure of the scFv version of this antibody was determined via crystallization (Thomas et al., 2002; PMID: 11679577).

Short Description

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.