Anti-Ca 19-9 [121SLE]

Catalogue Number: AB04318-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:121 SLE; sialyl Lewis a
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: 121SLE
Isotype: IgG
Immunogen: The original antibody was raised by immunizing a mouse with ten precipitin lines obtained after immunodiffusion using monoclonal antibody NS 19-9 and mucins isolated from an ovarian cyst of a OLe (a+b-) patient.
Application: ELISA, FC, ICC, IHC

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The original version of this antibody was used for immunohistochemistry on the normal gastrointestinal mucosa of Le-positive individuals (Herrero-Zabaleta et al., 1987; PMID:2444292), and on endometrial tissue specimens obtained in different phases of the menstrual cycle (Hey and Aplin., 1996; PMID:8910004). This antibody was used for an ELISA on carbohydrate proteins (Manimala et al., 2007; PMID:17483136), and on MUC1 samples (Hey and Aplin., 1996; PMID:8910004). Furthermore this antibody was used for immunocytochemistry on HT 29 tumour cells (Koehler et al., 2009; PMID:20010946). The original version of this antibody was used for flow cytometry on ovarian cancer cell line SW626 and SCLC cell line DMS79 (Ragupathi et al., 2009; PMID:19190907).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.