Anti-CD26 [134-2C2 ]
Catalogue Number: AB04333-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | DPP4; DPPIV; DPP IV; ADABP; ADCP-2; TP103; Dipeptidyl peptidase 4; Dipeptidyl peptidase IV; Adenosine deaminase complexing protein 2; T-cell activation antigen CD26 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 134-2C2 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing mice with a synthetic peptide from the amino terminal region of human CD26. |
| Application: | FC, IHC, FA |
Additional Text
Gene ID
1803
Gene Name
DPP4
Uniprot ID
P27487
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Short Description
This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.
Application Notes
This antibody was capable of increasing the proliferation of purified T cells in the presence of exogenous interleukin 2 (IL2) or phorbol 12-myristate 13-acetate (PMA) (Knapp W et al., Oxford University Press 1989;417-418). An increased IL2 secretion in T cells cultured with PMA plus 134-2C2 mAb was observed and Northern blot analysis showed that the mAb 134-2C2 acts synergistically with PMA favoring the induction of both IL2 and interferon-gamma mRNA synthesis, as well as the enhancement of IL2 receptor and transferrin receptor mRNA expression (PMID: 1673434). This antibody was used in the flow cytometric analysis of CD26 expression by nylon wool T cells and purified CD4+ and CD8+ lymphocyte subsets (PMID: 1356916). This antibody can also be used used for immunohistochemical analysis of CD26 in frozen tissue sections.
AB04333-1.1 Datasheet
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