Anti-CXCR4 [281F12]
Catalogue Number: AB04369-34.11-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | CXC-R4; CXCR-4; C-X-C chemokine receptor type 4; fusin; CD184; 2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS; WHIMS1; Leukocyte-derived seven transmembrane domain receptor |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Camelid |
| Clone: | 281F12 |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, FC |
Additional Text
Gene Name
CXCR4
Uniprot ID
P61073
Gene ID
7852
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The binding of the original version of this antibody (VHH) to CXCR4-expressing viral lipoparticles was characterized in an ELISA. Furthermore, it was analyzed for its ability to compete with the ligand CXCL12 (or SDF-1a) for receptor binding by displacement of biotinylated SDF-1 on Caki-CXCR4 cells in flow cytometry. This antibody exhibited medium/low potency (IC50 ≥ 10 nM). In its bi-specific construction with clone 57A07, it served a functional role (US20220242958).
AB04369-34.11 Datasheet
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