Catalogue Number: AB04370-34.11-BS-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin 3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Camelid |
| Clone: | 57A07 |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, FACS, FC |
IL3RA
3563
P26951
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (KD 0.783 nM). In a FACS binding assay, this antibody exhibited an EC50 of 0.66 nM, 1.3 nM, and 0.24 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC50 of 1.20 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958).