Anti-IL-3Ra [55A01]

Catalogue Number: AB04371-34.11-BS-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:VHH Nanobodies
Alias:CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin 3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Camelid
Clone: 55A01
Isotype:
Immunogen:
Application: ELISA, FACS, FC

Additional Text

Gene Name

IL3RA

Gene ID

3563

Uniprot ID

P26951

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (KD 17.1 nM). In a FACS binding assay, this antibody exhibited an EC50 of 8.2 nM, 11 nM, and 1.1 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC50 of 40.0 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958).