Anti-IL12RB1 [148C09]

Catalogue Number: AB04392-34.11-BS-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:VHH Nanobodies
Alias:CD212; IL12RB1#30; IL-12R-beta-1; IL-12RB1; Interleukin-12 receptor subunit beta-1; L-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12 receptor beta component
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Camelid
Clone: 148C09
Isotype:
Immunogen:
Application: ELISA, FACS, FC, Inh, SPR

Additional Text

Gene Name

IL12RB1

Gene ID

3594

Uniprot ID

P42701

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (KD 3.3 nM), ELISA (IC50 3.7 and 1.5 nM for IL-12 and IL-23, respectively), and FACS (EC50 1.3 nM). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958).