Anti-env, Envelope glycoprotein gp160 [Fab 58.2]
Catalogue Number: AB04427-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | gp120; Glycoprotein 120; Surface protein gp120 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | Fab 58.2 |
| Isotype: | IgG |
| Immunogen: | The original antibody was raised by immunizing a mouse with a 40 amino-acid cyclical peptide containing the entire V3 sequence of HIV-1 |
| Application: | ELISA, NT, InVitroA, Crstapy |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Uniprot ID
P05877
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The original antibody was used for an ELISA on repligen peptides containing V3 sequences. Further this antibody was used for a neutralization assay using 3 different HIV strains on CEM-SS cells. Here it was able to neutralize specific HIV strains (White-Scharf et al., 1993; PMID:7685962). The structure of the original antibody was determined using x-ray crystallography (Stanfield et al., 1999; PMID:10368281). This antibody was used for panning against a peptide display library (Jellis et al., 1993; PMID:7506691).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB04427-23.0-BT Datasheet
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