Anti-Envelope glycoprotein gp160 [0.5beta]
Catalogue Number: AB04428-3.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | env; Env polyprotein; Envelope glycoprotein gp160 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 0.5beta |
| Isotype: | IgG2b |
| Immunogen: | The original antibody was raised by immunizing a mouse with the glycoprotein fraction prepared from H9/HTLV IIIB cell extracts. |
| Application: | ELISA, WB, NT |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Uniprot ID
P03377
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The original version of this antibody was used for an ELISA on a synthetic 20 amino acid peptide (308-327) based on the sequence of the RP135 region of gp120 from HIV-IIIB (Maeda et al., 1991; PMID:1873503). This antibody was used for a western blot on HTLV-IIIB antigens (Matsushita et al., 1988; PMID:2452899), and on Purified HTLV-IIIB (Skinner et al., 1988; PMID:2456088). The NMR structure of this antibody was determined (Tugarinov et al., 2000; PMID:10801487). The ability of this antibody to neutralize a cell-free HIV infection of H9 cells was assayed. It was indeed able to prevent this infection (Matsushita et al., 1988; PMID:2452899). This antibody was also able to neutralize the HIV infection of AA-5 cells (Skinner et al., 1988; PMID:2456088). This antibody was able to prevent HIV infection in chimpanzees in vivo (Emini et al., 1992; PMID:1741059).
AB04428-3.0 Datasheet
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