Catalogue Number: AB04432-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | ORF2CP; VP1; Major capsid protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | A6.2 |
| Isotype: | IgG |
| Immunogen: | The original antibody was raised by immunizing a A MNV-1-seropositive 129 mouse with brain homogenate containing MNV-1. |
| Application: | ELISA, NT, InVitroA |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
The original antibody was used for an neutralization assay on the RAW 264.7 cells with the P-domain of MNV-1 (Taube et al., 2010; PMID:20335262). Further a plaque neutralization assay was performed on either MNV-1.CW1* or MNV-1CW1*.fab2 (Taube et al., 2010; PMID:20335262), on MNV-1 (Kolawole et al., 2014; PMID:24501415), and on MNV-1.CW1 or MNV-1 brain homogenate (Wobus et al., 2004; PMID:15562321). The structure of the original antibody was determined using cryo-EM (Taube et al., 2010; PMID:20335262). This antibody was used for an ELISA on CsCl-purified MNV-1 particles (Wobus et al., 2004; PMID:15562321).
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques.