Anti-Capsid protein [A6.2]

Catalogue Number: AB04432-23.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:ORF2CP; VP1; Major capsid protein
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone: A6.2
Isotype: IgG
Immunogen: The original antibody was raised by immunizing a A MNV-1-seropositive 129 mouse with brain homogenate containing MNV-1.
Application: ELISA, NT, InVitroA

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The original antibody was used for an neutralization assay on the RAW 264.7 cells with the P-domain of MNV-1 (Taube et al., 2010; PMID:20335262). Further a plaque neutralization assay was performed on either MNV-1.CW1* or MNV-1CW1*.fab2 (Taube et al., 2010; PMID:20335262), on MNV-1 (Kolawole et al., 2014; PMID:24501415), and on MNV-1.CW1 or MNV-1 brain homogenate (Wobus et al., 2004; PMID:15562321). The structure of the original antibody was determined using cryo-EM (Taube et al., 2010; PMID:20335262). This antibody was used for an ELISA on CsCl-purified MNV-1 particles (Wobus et al., 2004; PMID:15562321).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques.