Anti-Genome polyprotein [PVSS8A]
Catalogue Number: AB04488-34.11-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | Capsid protein VP1; Capsid protein VP2; Poliovirus type 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Camelid |
| Clone: | PVSS8A |
| Isotype: | |
| Immunogen: | The original antibody was raised by immunizing a dromedary with poliovirus type 1 Sabin strain. |
| Application: | NT, InVitroA, SPR |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Gene ID
919920
Gene Name
PVgp1
Uniprot ID
P03300
Application Notes
The binding strength of the original antibody to poliovirus antigens was determined using surface plasmon resonance (Thys et al., 2011; PMID:21371506). The original antibody was used for a neutralization assay against three types of poliovirus. This antibody showed neutralization in type 1 polioviruses. The cytotoxicity of this antibody on HeLa cells was also evaluated. It showed no cytotoxicity (Thys et al., 2010; PMID:20566349). The effect of this antibody on virus entry and uncoating was determined. It showed change in the behavior of the polio particles (Schotte et al., 2014; PMID:24501405). The structure of this antibody was determined using cryo-EM (Strauss et al., 2016; PMID:26764003).
AB04488-34.11 Datasheet
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