Anti-gB [1G2]
Catalogue Number: AB04495-10.29-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Envelope glycoprotein B; UL55; Ab-50 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Human |
| Clone: | 1G2 |
| Isotype: | |
| Immunogen: | The original antibody was isolated from EBV transformed human peripheral blood derived B cells derived from hCMV-infected donors. |
| Application: | ELISA, FACS, FC, IP, NT, InVitroA, SPR, Crstapy |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Uniprot ID
P13201
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The original version of the antibody was used in a neutralization assay against human cytomegalovirus (hCMV). It was found to neutralize hCMV with high potency - it neutralized the virus with an IC50 of 0.1 µg/ml and an IC90 of 0.4 µg/ml (US9346874B2). The Fab version of this antibody was generated and its structure in complex with hCMV gB was explored using crystallography. It was also used in neutralization assays, surface staining of full-length gB in flow cytometry, and gB immunoprecipitation (Chandramouli et al., 2015; PMID: 26365435).
Short Description
This reformatted human antibody was made using the variable domain sequences of the original Human IgG3 format, for improved compatibility with existing reagents, assays and techniques.
AB04495-10.29-BT Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations