Anti-gB [1G2]
Catalogue Number: AB04495-12.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Envelope glycoprotein B; UL55; Ab-50 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Human |
| Clone: | 1G2 |
| Isotype: | IgG3 |
| Immunogen: | The original antibody was isolated from EBV transformed human peripheral blood derived B cells derived from hCMV-infected donors. |
| Application: | ELISA, FACS, FC, IP, NT, InVitroA, SPR, Crstapy |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Uniprot ID
P13201
Application Notes
The original version of the antibody was used in a neutralization assay against human cytomegalovirus (hCMV). It was found to neutralize hCMV with high potency - it neutralized the virus with an IC50 of 0.1 µg/ml and an IC90 of 0.4 µg/ml (US9346874B2). The Fab version of this antibody was generated and its structure in complex with hCMV gB was explored using crystallography. It was also used in neutralization assays, surface staining of full-length gB in flow cytometry, and gB immunoprecipitation (Chandramouli et al., 2015; PMID: 26365435).
AB04495-12.1 Datasheet
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