Anti-FVIIa DVQ [mAb4F5]
Catalogue Number: AB04498-10.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | SPCA; Eptacog alfa; Proconvertin; Coagulation factor VII; EC:3.4.21.21; Blood coagulation factor VIIa; Serum prothrombin conversion accelerator |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | mAb4F5 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing mice with FVIIaDVQ. |
| Application: | SPR, Crstion |
Additional Text
Gene Name
F7
Uniprot ID
P08709
Gene ID
2155
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The binding affinity of original format of the antibody to FVIIaDVQ was measured by surface plasmon resonance (Kd= 32 pM). The crystal structure of the Fab fragment of the antibody was determined (Jiang et al., 2019; PMID: 31294329).
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB04498-10.0-BT Datasheet
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