Anti-HIV-1 surface protein gp120 [694-D]
Catalogue Number: AB04521-10.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Surface protein gp120; Envelope glycoprotein gp160; Env polyprotein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Human |
| Clone: | 694-D |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by Epstein-Barr virus transformation of peripheral blood mononuclear cells from HIV-seropositive individuals and screening for reactivity against the rgp120IIIB peptide. |
| Application: | ELISA, NT, IB |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Uniprot ID
P05877
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The original version of this antibody (human IgG1) was characterized for its specificity and reactivity using ELISA and IB assays. In the ELISA, it reacted with the V3 of HIV strains MN, SF-2, HXB2, RF, WM52, NY5, SC, and CDC4 with an affinity (Kd) of 1.8 µM and 12.0 µM for SF-2 and HXB2, respectively. In an IB, this antibody reacted with gp120HTLV-IIIB. In in vitro neutralization assays, this antibody exhibited neutralizing activity against multiple HIV-1 strains, exhibiting broad reactivity (US5914109A).
AB04521-10.0 Datasheet
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