Anti-Capsid protein VP1 [Nano-25]
Catalogue Number: AB04579-34.11-BS-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | CP; Capsid protein; ABCD_AG266 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Camelid |
| Clone: | Nano-25 |
| Isotype: | |
| Immunogen: | The original antibody was generated by immunizing a single alpaca with the GII.10 virus-like particle protein. |
| Application: | ELISA, EM, Crstapy |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
UniProt ID
Q5F4T5
Application Notes
The reactivity of the original antibody (alpaca VHH) against norovirus VLPs and P domains was determined using ELISA. Using isothermal titration calorimetry, a Kd of 28 nM was measured between the antibody and the GII.10 P domain. The crystal structure of this antibody in complex with norovirus GII.10 P domain was determined (Koromyslova & Hansman, 2015; PMID: 25520510). The epitope of this antibody was further characterized in X-ray crystallography and cryo-EM (Koromyslova & Hansman, 2017; PMID: 29095961).
AB04579-34.11-BS Datasheet
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