Anti-Flagellin protein [0A07]
Catalogue Number: AB04631-34.11-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | FliC; AbiSeO7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Camelid |
| Clone: | 0A07 |
| Isotype: | |
| Immunogen: | The original antibody was generated by immunizing alpacas with heat-inactivated Salmonella cells. |
| Application: | ELISA, Inh, InVitroA, InVivoA |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The original version of this antibody (alpaca VHH) exhibited the highest inhibition of intracellular S. enterica (strain Hadar 5643) growth out of all of the tested antibodies. In vitro, the antibody was evaluated for its ability to disrupt Salmonella colonization in chicken intestinal cultures, resulting in a significant 7.5-log reduction in Salmonella genome copy numbers in ileum sections. In vivo, it was tested for its protective efficacy in broiler chickens challenged with Salmonella enterica via oral gavage. The antibody significantly decreased Salmonella levels by 0.7 log10 in both jejunum and ileum compared to the control group when administered at three different time points post-challenge (US10421806B2).
AB04631-34.11 Datasheet
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