Anti-Avian influenza virus nucleoprotein [A65]
Catalogue Number: AB04650-34.11-BS-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | VHH Nanobodies |
| Alias: | Nucleocapsid protein |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 1 mg |
| Host name: | Camelid |
| Clone: | A65 |
| Isotype: | |
| Immunogen: | The original antibody was generated by immunizing alpacas with avian influenza virus nucleoprotein, creating the appropriate phage display library, and panning against the original target. |
| Application: | ELISA, InVivoA |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The binding specificity of the original camelid (alpaca) single-domain antibody (sdAb; VHH) was tested in an ELISA. This antibody was used to generate an anti-avian influenza nucleoprotein and anti-human IgA bi-specific construct together with Ab04649 [A8]. The bi-specific construct detected a range of influenza virus strains in ELISA, including low-virulence and vaccine strains. Namely, H1N1, H3N2, H5N3, H5N1 (LP), H7N3(LP), H8N4, H10N8, H11N6, H12N5, H2N2, H4N6, H5N9, H6N2, H7N7, H9N2, H10N7, H12N6, and H13N6. The bi-specific construct also exhibited a significantly prolonged stability in vivo in Balb/c mice compared to the sdAb version of the antibody (CN111116752B).
Uniprot ID
P26056
AB04650-34.11-BS Datasheet
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