Anti-IL-8 [YX20]

Catalogue Number: AB04989-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: YX20
Isotype: IgG
Immunogen: The original antibody was generated by immunizing New Zealand rabbits with recombinant human IL-8.
Application: ELISA, Inh

Additional Text

Uniprot ID

P10145

Gene ID

3576

Gene Name

CXCL8

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Specificity

IL8; Interleukin-8; CXCL8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor; 4-123-36

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody can be used for the detection of human IL-8 in a sample. A combination of YX40 and YX5 or YX20 can be for the detection of human CXCL1 in a sandwich assay, where YX40 was used as a coating antibody and biotinylated YX5 or YX20 was used as detection antibody. This antibody was capable of inhibit IL-8 mediated neutrophil chemotaxis in an in vitro assay. In vivo, this antibody was capable of inhibiting the growth of HCT116 tumor cells (colon tumor cells) in nude mice (CN115850473).