Catalogue Number: AB05003-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Group A Streptococcus M protein; group A streptococcal M protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 2E184 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing BALB/c mice with a conserved epitope of the GAS M protein-peptide 7-8-conjugated to KLH (7-8-KLH). |
| Application: | ELISA, LF, GIcA |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
The original antibody (mouse IgG1) was generated and confirmed to specifically recognize GAS M protein via ELISA. A colloidal gold-labeled version was successfully employed in a lateral flow assay (LFA) for GAS M protein detection. Additionally, it was used in a colloidal gold immunochromatographic assay (GICA) to detect multiple GAS M protein serotypes (M1, M3, M5, M6, M12, M18, and M24). A sensitivity evaluation using GICA determined a minimum detection limit of 8 x 10³ CFU/mL for serotype M6 Group A Streptococcus (CN118406142A).