Anti-GAS M protein [2E184]

Catalogue Number: AB05003-1.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Group A Streptococcus M protein; group A streptococcal M protein
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 2E184
Isotype: IgG1
Immunogen: The original antibody was generated by immunizing BALB/c mice with a conserved epitope of the GAS M protein-peptide 7-8-conjugated to KLH (7-8-KLH).
Application: ELISA, LF, GIcA

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The original antibody (mouse IgG1) was generated and confirmed to specifically recognize GAS M protein via ELISA. A colloidal gold-labeled version was successfully employed in a lateral flow assay (LFA) for GAS M protein detection. Additionally, it was used in a colloidal gold immunochromatographic assay (GICA) to detect multiple GAS M protein serotypes (M1, M3, M5, M6, M12, M18, and M24). A sensitivity evaluation using GICA determined a minimum detection limit of 8 x 10³ CFU/mL for serotype M6 Group A Streptococcus (CN118406142A).