Anti-NMDAR1 [007-168], Human IgG3, Fc Silent™, kappa

Catalogue Number: AB05048-12.4-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	NR1; NMD-R1; hNR1; GluN1; GRIN1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Human
Clone:	007-168
Isotype:	IgG3
Immunogen:	This antibody was raised from human cerebrospinal fluid samples.
Application:	ELISA, FC, IF, IHC, InVitroA

Overview
Datasheets

Additional Text

Gene Name

GRIN1

Gene ID

2902

Uniprot ID

Q05586

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody was used for immunofluorescence on NR1-transfected HEK cells. This antibody was used for flow cytometry on Hek cells, it showed positive staining. This antibody was used in vitro on human hippocampal neurons to determine the effect on calcium uptake, it showed a profoundly reduced NMDA-induced calcium influx (Kreye et al., 2016; PMID:27543972). This antibody was used for an ELISA on the GluN1 subunit bound to a Fc domain and the GluN1-GluN2A subunit bound to a Fc domain, it showed binding to both (Steinke et al., 2023; PMID:36866449). This antibody was used for immunohistochemistry on rat hippocampi, and mouse brains (Wagner et al., 2020; PMID:32735875, Jurek et al., 2019; PMID:31325344). This antibody was used for flow cytometry on NR1-EYFP-transfected HEK293 cells (Ly et al., 2018; PMID:30187160).

Short Description

This is a reformatted human IgG3 Fc Silent™ antibody, based on the original human IgG3 format, created for improved compatibility with existing reagents, assays and techniques.

AB05048-12.4 Datasheet

Price

£430.00

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