Anti-CCL2 [3.11.2], Mouse IgG1, kappa

Catalogue Number: AB05049-1.1-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	MCP1; MCP-1; HC11; MCAF; SCYA2; C-C motif chemokine 2; Small-inducible cytokine A2; Monocyte secretory protein JE; Monocyte chemotactic protein 1; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	3.11.2
Isotype:	IgG1
Immunogen:	This antibody was raised by immunizing XenoMouse mouse with the human MCP-1 peptide QPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT.
Application:	ELISA, WB, InVitroA, SPR

Overview
Datasheets

Additional Text

Uniprot ID

P13500

Gene Name

CCL2

Gene ID

6347

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Application Notes

This antibody was used for an ELISA on human MCP-1, it showed binding. This antibody was tested in vitro on THP-1 cells for its ability to neutralize MCP1, it showed it was able to neutralize MCP-1, the concentration of antibody that yielded a 50% decrease in MCP-1 induced fluorescence intensity is 0.092 ug/mL. This antibody was used for surface plasmon resonance on human MCP-1. This antibody was used for a western blot on the human MCP-1 protein, to determine its epitope, it was shown that this antibody binds to a conformational epitope (US7687606B2).

AB05049-1.1 Datasheet

Price

£430.00

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