Anti-Factor VIII [NBA3], Mouse IgG1, kappa

Catalogue Number: AB05134-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:AHF; Coagulation factor VIII; Antihemophilic factor; Procoagulant component
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: NBA3
Isotype: IgG1
Immunogen: This antibody was raised from PMBCs from a hemophilia A patient with inhibitor LE.
Application: ELISA, FA

Additional Text

Gene Name

F8

Uniprot ID

P00451

Gene ID

2157

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Application Notes

This antibody was used for an ex vivo whole blood assay, it showed neutralizing activity only in this assay with an IC50 of 4-6 umol/mL. This antibody was used for an ELISA on factor VIII (Coxon et al., 2021; PMID:33973229).