Anti-CD206 [antibody 83 ], Rabbit IgG, kappa
Catalogue Number: AB05157-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | MMR; Macrophage mannose receptor 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | antibody 83 |
| Isotype: | IgG |
| Immunogen: | The original antibody was generated by immunizing CD206-deficient mice with a mixture of the CD206 antigen and an adjuvant. |
| Application: | ELISA, FACS, FC |
Additional Text
Gene Name
MRC1
UniProt ID
Q61830
Gene ID
17533
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Application Notes
The specificity of the original format of the antibody was confirmed by ELISA analysis. The original format of the antibody showed a cytotoxic effect on CD206-positive M2 macrophages in biological tissues. In particular, it showed a significant decrease in CD206-positive M2 macrophages in the visceral fat and subcutaneous fat by FACS analysis. When the original format of the antibody was administrated to mice under a high-fat diet, it showed an improvement in the glucose tolerance disorder and insulin resistance (WO2022244854A).
AB05157-23.0 Datasheet
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