anti-Pam-Igloo-L, anti Periplaneta Americana Igloo L 1-75, rabbit, polyclonal
Catalogue Number: ABD-060-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, ICC |
Description
Description: Axogenesis and synaptic signal transmission in the vertebrate nervous system are based on the abundant expression of the growth-associated protein GAP-43. In non-vertebrates a GAP-43 related gene (igloo, invertebrate GAP-43 like) was found in Drosophila and encodes two proteins, IGLOO-L and IGLOO-S, with sequence homology and similar biochemical activity to GAP-43. We have cloned a GAP-43-like gene in a holometabolic insect, the American cockroach, Periplaneta americana. As for Drosophila, we found two putative pigl mRNAs, pigl-L and pigl-S, in the cockroach (Fig. 1). Immunocytochemical investigations with a antiserum to Pam-Igl L and Pam-Igl S provide a function for Pam-Igloo L in establishment or maintenance of synaptic contacts and can help to understand the ongoing expression of GAP-43 in the mature nervous system (Haenold,2004).
Additional Text
Application Notes
Anti-Pam-Igloo-L can be used for ELISA and Immunocytochemistry.
ABD-060 MSDS
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