Cleaved PARP Monoclonal Antibody

Catalogue Number: ABM0043-ABK

Manufacturer:Abbkine
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Alias:PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Synthetic Peptide
Application: WB

Description

Description: PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly (ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Additional Text

Gene Name

PARP1

Uniprot ID

P09874

Concentration

1 mg/ml

Gene ID

142

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Short Description

Mouse Anti-Cleaved PARP Monoclonal Antibody

Molecular Weight

116, 89 KD