anti-HIgG(Fc)-N-DM1 ADC

Catalogue Number: ADC-AA-008-CRB

Manufacturer:Creative BioLabs
Physical state:Solution
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 50 ug

Additional Text

Storage Note

-20°C

Short Description

This ADC product is comprised of an anti-human IgG Fc specific polyclonal antibody conjugated via a noncleavable linker to DM1. The antibody portion is a secondary antibody and the drug portion, DM1, is a cytotoxic small molecule which binds to tubulins, interrupts microtubule dynamics, and induces cell death. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.