Catalogue Number: ADC-AA-016-CRB
| Manufacturer: | Creative BioLabs |
| Physical state: | Solution |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
-20°C
This ADC product is comprised of a Fab fragment of an anti-human IgG Fc specific polyclonal antibody conjugated via a noncleavable linker to Alfa-amanitin. The antibody portion is a Fab fragment of a secondary antibody and the drug portion, Alfa-amanitin, is a cytotoxic small molecule which binds to RNA, causes RNA damage. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.