Protein G-VC-MMAE ADC

Catalogue Number: ADC-AA-048-CRB

Manufacturer:	Creative BioLabs
Physical state:	Solution
Type:	Protein G Products
Shipping Condition:	Blue Ice
Unit(s):	10 uM

Overview
Datasheets

Additional Text

Storage Note

-20°C

Short Description

This ADC product is comprised of a Protein G conjugated via a VC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening monoclonal antibodies as ADC candidates.

ADC-AA-048 Datasheet

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