Functional TRAIL-R1 (human) Antibody, mAb(preservative free)
Catalogue Number: ADP0012-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | TRAIL Receptor 1; DR4; APO2; TNFRSF10A; CD261 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | |
| Clone: | HS101 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, ICC, IP |
Description
Description: TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
Additional Text
Gene Name
TNFRSF10A
Concentration
1 mg/ml
Uniprot ID
O00220
Gene ID
8797
Antibody Clonality
Monoclonal
ADP0012 Datasheet
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