Catalogue Number: ADP0013-ABG
Manufacturer: | Abcepta |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | TRAIL Receptor 2; DR5; KILLER; TNFRSF10B; CD262 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug |
Host name: | |
Clone: | HS201 |
Isotype: | |
Immunogen: | |
Application: | FC, ICC, IHC-P, IP |
Description: TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
TNFRSF10B
O14763
1 mg/ml
8795
Monoclonal