Catalogue Number: AF0014-AFF
Manufacturer: | Affinity Biosciences Ltd |
Shelf Life: | 12 months |
Preservative: | 0.02% sodium azide |
Molecular Weight: | 25 kDa |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | CD28 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 200 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | A synthesized peptide derived from human CD28, corresponding to a region within C-terminal amino acids. |
Application: | WB, IHC |
Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).
1 mg/ml
940
25 kDa
CD28
P10747
Affinity Purified
Polyclonal
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. .