CD28 Antibody

Catalogue Number: AF0014-AFF

Manufacturer:Affinity Biosciences Ltd
Shelf Life:12 months
Preservative:0.02% sodium azide
Molecular Weight:25 kDa
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:CD28
Shipping Condition:Blue Ice
Unit(s): 100 ul, 200 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthesized peptide derived from human CD28, corresponding to a region within C-terminal amino acids.
Application: WB, IHC

Description

Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).

Additional Text

Concentration

1 mg/ml

Gene ID

940

Molecular Weight

25 kDa

Gene Name

CD28

Uniprot ID

P10747

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Storage Note

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. .

Price
£212.00


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