Goat Anti-ABCD3 Antibody
Catalogue Number: AF1012A-ABG
AF1012a Image
AF1012a Image
AF1012a Image
AF1012a Image
AF1012a Image
AF1012a (0.2 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
AF1012a Image
AF1012a (3.8 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
AF1012a Image
EB08710 (3.8µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
AF1012a Image
EB08710 Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fol
| Manufacturer: | Abcepta |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | ATP-binding cassette sub-family D member 3, 70 kDa peroxisomal membrane protein, PMP70, ABCD3, PMP70, PXMP1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IHC, pELISA |
Description
Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Additional Text
Gene Name
ABCD3
Uniprot ID
P28288
Gene ID
5825
Antigen Type
Synthetic Peptide
Accession Number
NP_002849
Antibody Clonality
Polyclonal
Short Description
Peptide-affinity purified goat antibody
Concentration
0.5 ug/ml
AF1012a Datasheet
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