Goat Anti-ADRA2A Antibody

Catalogue Number: AF1031A-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, ADRA2A, ADRA2R, ADRAR
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype:
Immunogen:
Application: ELISA, ICC, IF

Description

Description: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Additional Text

Gene Name

ADRA2A

Uniprot ID

P08913

Gene ID

150

Antigen Type

Synthetic Peptide

Accession Number

NP_000672

Antibody Clonality

Polyclonal

Short Description

Peptide-affinity purified goat antibody

Concentration

0.5 ug/ml