Goat Anti-COX1 / PTGS1 Antibody
Catalogue Number: AF1270A-ABG
AF1270a Image
AF1270a Image
AF1270a Image
AF1270a staining (1 µg/ml) of HeLa lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
AF1270a Image
AF1270a (3.8 µg/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
| Manufacturer: | Abcepta |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Prostaglandin G/H synthase 1, 1.14.99.1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1, PTGS1, COX1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | WB, IHC, pELISA |
Description
Description: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Additional Text
Gene Name
PTGS1
Uniprot ID
P23219
Gene ID
5742
Antigen Type
Synthetic Peptide
Antibody Clonality
Polyclonal
Accession Number
NP_542158
Short Description
Peptide-affinity purified goat antibody
Concentration
0.5 ug/ml
AF1270a Datasheet
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