Goat Anti-Fumarase / FH Antibody
Catalogue Number: AF1449A-ABG
AF1449a Image
AF1449a Image
AF1449a Image
AF1449a Image
AF1449a Image
EB7874 (1.5ug/ml) as the reporter with EB002023 as the capture rabbit antibody (2ug/ml).
AF1449a Image
AF1449a (0.01µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
AF1449a Image
AF1449a (3.75µg/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
AF1449a Image
AF1449a (3.75µg/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
| Manufacturer: | Abcepta |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Fumarate hydratase, mitochondrial, Fumarase, 4.2.1.2, FH |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | WB, IHC, pELISA |
Description
Description: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Additional Text
Gene Name
FH
Gene ID
2271
Uniprot ID
P07954
Accession Number
NP_000134
Antigen Type
Synthetic Peptide
Antibody Clonality
Polyclonal
Short Description
Peptide-affinity purified goat antibody
Concentration
0.5 ug/ml
AF1449a Datasheet
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