Fumarase / FH, Biotinylated
Catalogue Number: AF1449B-ABG
| Manufacturer: | Abcepta |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Fumarate hydratase, mitochondrial, Fumarase, 4.2.1.2, FH |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | WB, pELISA |
Description
Description: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Additional Text
Antigen Type
Synthetic Peptide
Gene ID
2271
Gene Name
FH
Accession Number
NP_000134
Uniprot ID
P07954
Antibody Clonality
Polyclonal
Short Description
Peptide-affinity purified goat antibody
Concentration
0.5 ug/ml
AF1449B Datasheet
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