Goat Anti-MRP8 / ABCC11 Antibody

Catalogue Number: AF1684A-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8, ABCC11, MRP8
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype:
Immunogen:
Application: FC, IF, WB, IHC, pELISA

Description

Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.

Additional Text

Gene ID

85320

Uniprot ID

Q96J66

Concentration

0.5 mg/ml

Gene Name

ABCC11

Antigen Type

Synthetic Peptide

Antibody Clonality

Polyclonal

Accession Number

NP_660187

Short Description

Peptide-affinity purified goat antibody