Catalogue Number: AF1907A-ABG
| Manufacturer: | Abcepta |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Ran-specific GTPase-activating protein, Ran-binding protein 1, RanBP1, RANBP1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, WB, IHC, pELISA |
Description: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
5902
NP_002873
RANBP1
P43487
Synthetic Peptide
Polyclonal
Peptide-affinity purified goat antibody
0.5 ug/ml