Goat Anti-RANBP1 Antibody

Catalogue Number: AF1907A-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Ran-specific GTPase-activating protein, Ran-binding protein 1, RanBP1, RANBP1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype:
Immunogen:
Application: FC, IF, WB, IHC, pELISA

Description

Description: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Additional Text

Gene ID

5902

Accession Number

NP_002873

Gene Name

RANBP1

Uniprot ID

P43487

Antigen Type

Synthetic Peptide

Antibody Clonality

Polyclonal

Short Description

Peptide-affinity purified goat antibody

Concentration

0.5 ug/ml