Catalogue Number: AF5407-AFF
Manufacturer: | Affinity Biosciences Ltd |
Shelf Life: | 12 months |
Preservative: | Azide |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | GAB2 KIAA0571 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 200 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | A synthesized peptide derived from human Gab2, corresponding to a region within C-terminal amino acids. |
Application: | WB, pELISA |
Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
1 mg/ml
9846
GAB2
Q9UQC2
74 kDa
Affinity Purified
Polyclonal