Caveolin 2 Antibody
Catalogue Number: AF5409-AFF
| Manufacturer: | Affinity Biosciences Ltd |
| Shelf Life: | 12 months |
| Preservative: | 0.02% sodium azide |
| Molecular Weight: | 27 kDa |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | CAV2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 200 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human Caveolin 2, corresponding to a region within N-terminal amino acids. |
| Application: | ICC, IF, WB, pELISA |
Description
Description: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Additional Text
Gene Name
CAV2
Uniprot ID
P51636
Concentration
1 mg/ml
Gene ID
858
Molecular Weight
27 kDa
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Storage Note
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
AF5409 Datasheet
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