Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody - With BSA and Azide
Catalogue Number: AH10795-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, 1.14.18.-, Catalase B, Glycoprotein 75, Melanoma antigen gp75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1, TYRP1, CAS2, TYRP, TYRRP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug, 100 ug |
| Host name: | Mouse |
| Clone: | SPM456 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, IHC-Fr |
Description
Description: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Additional Text
Gene ID
7306
Gene Name
TYRP1
Uniprot ID
P17643
Antibody Clonality
Monoclonal
Short Description
Mouse Monoclonal Antibody [Clone SPM456 ]
AH10795 Datasheet
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