CD8A (Anti-Mouse) (Cytotoxic / Suppressor T-Cell Marker) Antibody - With BSA and Azide
Catalogue Number: AH10904-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug, 100 ug |
| Host name: | Rat |
| Clone: | IBL-3/25 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: Recognizes a protein of 32kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8+ T-cells expresses CD8 as heterodimer. Some subpopulation of CD8+ T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase.
Additional Text
Gene Name
CD8A
Gene ID
12525
Uniprot ID
P01731
Antibody Clonality
Monoclonal
Short Description
Rat Monoclonal Antibody [Clone IBL-3/25 ]
AH10904 Datasheet
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