Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody - With BSA and Azide
Catalogue Number: AH10986-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug, 100 ug |
| Host name: | Mouse |
| Clone: | SPM594 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, IHC |
Description
Description: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Additional Text
Gene Name
CDH16
Uniprot ID
O75309
Gene ID
1014
Antibody Clonality
Monoclonal
Short Description
Mouse Monoclonal Antibody [Clone SPM594 ]
AH10986 Datasheet
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