p21WAF1 (Tumor Suppressor Protein) Antibody - With BSA and Azide
Catalogue Number: AH10990-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, MDA-6, p21, CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug, 100 ug |
| Host name: | Mouse |
| Clone: | DCS-60.2 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, WB, IHC |
Description
Description: This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Additional Text
Gene Name
CDKN1A
Uniprot ID
P38936
Gene ID
1026
Antibody Clonality
Monoclonal
Short Description
Mouse Monoclonal Antibody [Clone DCS-60.2 ]
AH10990 Datasheet
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