CD55 / Decay Accelerating Factor (DAF) Antibody - With BSA and Azide
Catalogue Number: AH11138-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Complement decay-accelerating factor, CD55, CD55, CR, DAF |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug, 100 ug |
| Host name: | Mouse |
| Clone: | 143-30 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, IHC-Fr |
Description
Description: Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
Additional Text
Gene ID
1604
Uniprot ID
P08174
Gene Name
CD55
Antibody Clonality
Monoclonal
Short Description
Mouse Monoclonal Antibody [Clone 143-30 ]
AH11138 Datasheet
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