PKM / Pyruvate Kinase Antibody
Catalogue Number: ALS11751-ABG
| Manufacturer: | Abcepta |
| Molecular Weight: | 57937 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Pyruvate kinase PKM, 2.7.1.40, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Goat |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, IHC-P, IP, WB |
Description
Description: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Additional Text
Concentration
10 mg/mL
Gene Name
PKM
Gene ID
5315
Uniprot ID
P14618
Molecular Weight
57937
Storage Note
+4°C or -20°C, Avoid repeated freezing and thawing.
Short Description
Goat Polyclonal Antibody
Purification
Purified
Antibody Clonality
Polyclonal
ALS11751 Datasheet
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