ITGB2 / CD18 Antibody (clone MEM-48)
Catalogue Number: ALS11971-ABG
| Manufacturer: | Abcepta |
| Molecular Weight: | 84791 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | MEM-48 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IHC-P, IP, WB, IHC-Fr, FA |
Description
Description: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
Additional Text
Gene Name
ITGB2
Uniprot ID
P05107
Concentration
0.5 mg/ml
Gene ID
3689
Molecular Weight
84782
Storage Note
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Short Description
Mouse Monoclonal Antibody
Purification
Protein A purified
Antibody Clonality
Monoclonal
ALS11971 Datasheet
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