CD225 / IFITM1 Antibody (C-Terminus)

Catalogue Number: ALS13946-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Interferon-induced transmembrane protein 1, Dispanin subfamily A member 2a, DSPA2a, Interferon-induced protein 17, Interferon-inducible protein 9-27, Leu-13 antigen, CD225, IFITM1, CD225, IFI17
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype:
Immunogen:
Application: ELISA, IHC-P, WB

Description

Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

Additional Text

Gene Name

IFITM1

Uniprot ID

P13164

Concentration

1 mg/ml

Gene ID

8519

Antigen Type

Synthetic Peptide

Molecular Weight

13964

Storage Note

Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Short Description

Rabbit Polyclonal Antibody

Purification

Affinity Purified

Antibody Clonality

Polyclonal