CD44 Antibody (clone IM7)

Catalogue Number: ALS14134-ABG

Manufacturer:Abcepta
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rat
Clone: IM7
Isotype:
Immunogen:
Application: FC, ICC, IHC-P, IP, WB, IHC-Fr

Description

Description: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Additional Text

Gene Name

CD44

Concentration

1 mg/ml

Gene ID

960

Uniprot ID

P16070

Molecular Weight

81538

Storage Note

Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.

Purification

Protein G purified

Short Description

Rat Monoclonal Antibody

Specificity

CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

Antibody Clonality

Monoclonal